Transgenic Animals Examples Ppt
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Transgenic animals examples ppt. A transgenic animal is animal whose chromosomes have been changed to carry the. This results in the second organism and its descendants being grouped as transgenic animals cloned organisms. Transgenic animals are created by deliberately inserting a gene into the genome of an animal.
Organisms containing integrated sequences of cloned DNA transgenes transferred using techniques of genetic engineering to include those of gene transfer and gene substitution are called transgenic animals. In this the udder cells from a 6-year-old Finn Dorset white sheep were injected into an unfertilized egg from a Scottish Blackface ewe which had its nucleus removed. Recombinant DNA methodology is used to construct the gene that is intended to express desirable qualities during the growth and development of the recipient animal.
Dolly the sheep was the first mammal to be cloned from an adult cell. Transgenic models are more precise in comparison to traditional animal models for example the oncomouse with its increased susceptibility to tumor development enables results for carcinogenicity studies to be obtained within a shorter time-frame thus reducing the course of tumor development in experimentally affected animals. Foreign genes are inserted into the germ line of the animal so it can be transmitted to the progeny.
Transgenic animals 1. Transgenic animals are used as tools in research and for the production of recombinant proteins The main applications of transgenic animals are described as followsStudying gene function. In the interest of educating the public about transgenic animals and determining their effect on society the methods of creating transgenic animals is discussed.
Mehendale in Encyclopedia of Toxicology Third Edition 2014 Abstract. The development of transgenic animals has been part of biotechnology research which has been expanding rapidly. Transgenesis is the procedure through which genetic information DNA or RNA is transferred from one organism to another.
For example Japanese medaka Oryzias latipes and zebrafish Barchydanio rerio have short life cycles 3 months from. Transgenic animals can be used as disease models transpharmers xenotransplanters food sources and other biological models. This lecture explains about the principle behind the transgenic animal production.
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