Transgenic Animals Applications Ppt

Transgenic Animals Synthetic modified or other foreign genes can be introduced into animals and plants and the resulting transgenic organisms can be used to study the function of the genes for example by insertional mutagenesis to produce novel products or to serve as animal models for studies of inherited human diseases.

Transgenic animals applications ppt. Applications Transgenic models for Alzheimer disease amyotrophic lateral sclerosis Huntington disease arthritis muscular dystrophy tumorigenesis hypertension neurodegenerative disorders endocrinological dysfunction coronary disease etc. These bacteria contained genetic information from a variety of different species. By DAMARIS BENNY DANIEL II Msc.

Transgenic animals can be used as disease models transpharmers xenotransplanters food sources and other biological models. Foreign genes are inserted into the germ line of the animal so it can be transmitted to the progeny. Transgenic animals 1.

The creations of many transgenic animals were subsequently reported in 1985s 6. Transgenic animals are used as tools in research and for the production of recombinant proteins The main applications of transgenic animals are described as followsStudying gene function. Transgenic animals ie engineered to carry genes from other species have the potential to improve human welfare.

One of them is the ability to engineer transgenic animals. DNA Technology Biotechnology The use or alteration of cells or biological molecules for specific applications Transgenics Transgenic changed genes Recombinant DNA DNA from different species mixed together Natural or man-made Whole organisms or cells Possible because the genetic code is universal All life uses the same genetic code ATGC Amplifying DNA Need. Industry and medicine have taken advantage of these animals a lot.

The development of transgenic animals has been part of biotechnology research which has been expanding rapidly. One of the most exciting prospects for the genetic manipulation of chickens is the potential development of an embryonic stem ES-cell system. Animal egg stage is also developed19 There are Since than many models have developed other models like beta receptor knockout mouse Rosenstiel et al gives summary of 32 transgenic uncoupling protein UCP1 knockout mouseacute murine HIVAN models developed.

Transgenic animals produced with. Organisms containing integrated sequences of cloned DNA transgenes transferred using techniques of genetic engineering to include those of gene transfer and gene substitution are called transgenic animals. 4 and in 1980s the transgenic mice is produced using the most popular microinjection technique 5.